Inhibition of monocarboxylate transporters (MCT) 1 and 4 reduces exercise capacity in mice

Abstract The concept of lactate shuttle is widely accepted in exercise physiology. Lactate transport is mediated by monocarboxylate transporters (MCT), which enable cells to take up and release lactate. However, the role of lactate during exercise has not yet been fully elucidated. In this study, we...

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Bibliographic Details
Main Authors: Yu Kitaoka, Kenya Takahashi, Hideo Hatta
Format: Article
Language:English
Published: Wiley 2022-09-01
Series:Physiological Reports
Subjects:
Online Access:https://doi.org/10.14814/phy2.15457