Low-level alternative tRNA priming of reverse transcription of HIV-1 and SIV in vivo

Low-level alternative tRNA priming of reverse transcription of HIV-1 and SIV in vivo

Abstract Background Reverse transcription (RT) of HIV and SIV is initiated by the binding of the acceptor stem of tRNALys3 to the primer binding site (PBS) of the viral RNA genome. Previous studies have suggested that this tRNALys3 is not the only molecule capable of priming reverse transcription, a...

पूर्ण विवरण

ग्रंथसूची विवरण
मुख्य लेखकों: Christine M. Fennessey, Celine Camus, Taina T. Immonen, Carolyn Reid, Frank Maldarelli, Jeffrey D. Lifson, Brandon F. Keele
स्वरूप: लेख
भाषा:English
प्रकाशित: BMC 2019-04-01
श्रृंखला:Retrovirology
विषय:
SIV
HIV
Primer binding site
tRNA
Next-generation deep-sequencing
ऑनलाइन पहुंच:http://link.springer.com/article/10.1186/s12977-019-0473-2

इंटरनेट

http://link.springer.com/article/10.1186/s12977-019-0473-2

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