HMGB1 Promotes In Vitro and In Vivo Skeletal Muscle Atrophy through an IL-18-Dependent Mechanism

HMGB1 Promotes In Vitro and In Vivo Skeletal Muscle Atrophy through an IL-18-Dependent Mechanism

Skeletal muscle atrophy occurs due to muscle wasting or reductions in protein associated with aging, injury, and inflammatory processes. High-mobility group box-1 (HMGB1) protein is passively released from necrotic cells and actively secreted by inflammatory cells, and is implicated in the pathogene...

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Bibliographic Details
Main Authors: Trung-Loc Ho, Chih-Hsin Tang, Sunny Li-Yun Chang, Chun-Hao Tsai, Hsien-Te Chen, Chen-Ming Su
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Cells
Subjects:
HMGB1
IL-18
inflammation
myogenesis
skeletal muscle atrophy
Online Access:https://www.mdpi.com/2073-4409/11/23/3936

Internet

https://www.mdpi.com/2073-4409/11/23/3936

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