The primary role of sebum in the pathophysiology of acne vulgaris and its therapeutic relevance in acne management

AbstractBackground Sebum physiology and its contributions to acne vulgaris (AV) pathophysiology have been long debated. Within the pilosebaceous unit, androgens drive sebocyte production of sebum, comprising mono-, di-, and triglycerides (the latter converted to fatty acids); squalene; cholesterol;...

Full description

Bibliographic Details
Main Authors: James Q. Del Rosso, Leon Kircik
Format: Article
Language:English
Published: Taylor & Francis Group 2024-12-01
Series:Journal of Dermatological Treatment
Subjects:
Online Access:https://www.tandfonline.com/doi/10.1080/09546634.2023.2296855