Topical Skullcapflavone II attenuates atopic dermatitis in a mouse model by directly inhibiting associated cytokines in different cell types

Topical Skullcapflavone II attenuates atopic dermatitis in a mouse model by directly inhibiting associated cytokines in different cell types

Skullcapflavone II (SFII), a flavonoid derived from Scutellaria baicalensis, is an anticancer agent. We aimed to validate SFII for atopic dermatitis (AD) therapy by demonstrating the anti-inflammatory effects of SFII in an AD mouse model produced by the topical application of the vitamin D3 analog M...

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Bibliographic Details
Main Authors: Youngae Lee, Jang-Hee Oh, Na Li, Hyun-Jae Jang, Kyung-Seop Ahn, Sei-Ryang Oh, Dong Hun Lee, Jin Ho Chung
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-12-01
Series:Frontiers in Immunology
Subjects:
Skullcapflavone II
atopic dermatitis
pruritus
Th2 cytokines
IgE
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.1064515/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.1064515/full

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