Regulation of Reactive Oxygen Species and the Antioxidant Protein DJ-1 in Mastocytosis.

Regulation of Reactive Oxygen Species and the Antioxidant Protein DJ-1 in Mastocytosis.

Neoplastic accumulation of mast cells in systemic mastocytosis (SM) associates with activating mutations in the receptor tyrosine kinase KIT. Constitutive activation of tyrosine kinase oncogenes has been linked to imbalances in oxidant/antioxidant mechanisms in other myeloproliferative disorders. Ho...

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Bibliographic Details
Main Authors: Do-Kyun Kim, Michael A Beaven, Joseph M Kulinski, Avanti Desai, Geethani Bandara, Yun Bai, Calman Prussin, Lawrence B Schwartz, Hirsh Komarow, Dean D Metcalfe, Ana Olivera
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5017616?pdf=render

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http://europepmc.org/articles/PMC5017616?pdf=render

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