Mechanisms of action and in vivo antibacterial efficacy assessment of five novel hybrid peptides derived from Indolicidin and Ranalexin against Streptococcus pneumoniae

Background Antimicrobial peptides (AMPs) are of great potential as novel antibiotics for the treatment of broad spectrum of pathogenic microorganisms including resistant bacteria. In this study, the mechanisms of action and the therapeutic efficacy of the hybrid peptides were examined. Methods TEM,...

Full description

Bibliographic Details
Main Authors: Hassan Mahmood Jindal, Keivan Zandi, Kien Chai Ong, Rukumani Devi Velayuthan, Sara Maisha Rasid, Chandramathi Samudi Raju, Shamala Devi Sekaran
Format: Article
Language:English
Published: PeerJ Inc. 2017-10-01
Series:PeerJ
Subjects:
Online Access:https://peerj.com/articles/3887.pdf