The Angiocrine Factor Rspondin3 Is a Key Determinant of Liver Zonation

Liver zonation, the spatial separation of different metabolic pathways along the liver sinusoids, is fundamental for proper functioning of this organ, and its disruption can lead to the development of metabolic disorders such as hyperammonemia. Metabolic zonation involves the induction of β-catenin...

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Bibliographic Details
Main Authors: Ana Sofia Rocha, Valerie Vidal, Marjolijn Mertz, Timothy J. Kendall, Aurelie Charlet, Hitoshi Okamoto, Andreas Schedl
Format: Article
Language:English
Published: Elsevier 2015-12-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124715012383