Robust model-based analysis of single-particle tracking experiments with Spot-On

Single-particle tracking (SPT) has become an important method to bridge biochemistry and cell biology since it allows direct observation of protein binding and diffusion dynamics in live cells. However, accurately inferring information from SPT studies is challenging due to biases in both data analy...

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Bibliographic Details
Main Authors: Anders S Hansen, Maxime Woringer, Jonathan B Grimm, Luke D Lavis, Robert Tjian, Xavier Darzacq
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2018-01-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/33125