Development of a diagnostic and risk prediction model for Alzheimer’s disease through integration of single-cell and bulk transcriptomic analysis of glutamine metabolism
BackgroundIn this study, we present a novel system for quantifying glutamine metabolism (GM) to enhance the effectiveness of Alzheimer’s disease (AD) diagnosis and risk prediction.MethodsSingle-cell RNA sequencing (scRNA-seq) analysis was utilized to comprehensively assess the expression patterns of...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2023-11-01
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Series: | Frontiers in Aging Neuroscience |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/fnagi.2023.1275793/full |