Sex- and age-dependent contribution of System xc– to cognitive, sensory, and social behaviors revealed by comprehensive behavioral analyses of System xc– null mice

BackgroundSystem xc– (Sxc–) is an important heteromeric amino acid cystine/glutamate exchanger that plays a pivotal role in the CNS by importing cystine into cells while exporting glutamate. Although certain behaviors have been identified as altered in Sxc– null mutant mice, our understanding of the...

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Bibliographic Details
Main Authors: Carla Frare, Shannon K. Pitt, Sandra J. Hewett
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-08-01
Series:Frontiers in Behavioral Neuroscience
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fnbeh.2023.1238349/full