Differences in gene expression and cytokine production by crystalline vs. amorphous silica in human lung epithelial cells

<p>Abstract</p> <p>Background</p> <p>Exposure to respirable crystalline silica particles, as opposed to amorphous silica, is associated with lung inflammation, pulmonary fibrosis (silicosis), and potentially with lung cancer. We used Affymetrix/GeneSifter microarray ana...

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Bibliographic Details
Main Authors: Perkins Timothy N, Shukla Arti, Peeters Paul M, Steinbacher Jeremy L, Landry Christopher C, Lathrop Sherrill A, Steele Chad, Reynaert Niki L, Wouters Emiel FM, Mossman Brooke T
Format: Article
Language:English
Published: BMC 2012-02-01
Series:Particle and Fibre Toxicology
Online Access:http://www.particleandfibretoxicology.com/content/9/1/6