Differences in gene expression and cytokine production by crystalline vs. amorphous silica in human lung epithelial cells

Differences in gene expression and cytokine production by crystalline vs. amorphous silica in human lung epithelial cells

<p>Abstract</p> <p>Background</p> <p>Exposure to respirable crystalline silica particles, as opposed to amorphous silica, is associated with lung inflammation, pulmonary fibrosis (silicosis), and potentially with lung cancer. We used Affymetrix/GeneSifter microarray ana...

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Bibliographic Details
Main Authors: Perkins Timothy N, Shukla Arti, Peeters Paul M, Steinbacher Jeremy L, Landry Christopher C, Lathrop Sherrill A, Steele Chad, Reynaert Niki L, Wouters Emiel FM, Mossman Brooke T
Format: Article
Language:English
Published: BMC 2012-02-01
Series:Particle and Fibre Toxicology
Online Access:http://www.particleandfibretoxicology.com/content/9/1/6

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