A mechanism linking ferroptosis and ferritinophagy in melatonin-related improvement of diabetic brain injury

Summary: Ferroptosis and ferritinophagy play critical roles in various disease contexts. Herein, we observed that ferroptosis and ferritinophagy were induced both in the brains of mice with diabetes mellitus (DM) and neuronal cells after high glucose (HG) treatment, as evidenced by decreases in GPX4...

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Bibliographic Details
Main Authors: Jiaojiao Yu, Yu Zhang, Qin Zhu, Zhengrui Ren, Mengting Wang, Sasa Kong, Hongbo Lv, Tao Xu, Zhaoyu Xie, Han Meng, Jun Han, Hui Che
Format: Article
Language:English
Published: Elsevier 2024-04-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004224007326