Effect of Polar Head Group Modifications on the Tumor Retention of Phospholipid Ether Analogs: Role of the Quaternary Nitrogen

Effect of Polar Head Group Modifications on the Tumor Retention of Phospholipid Ether Analogs: Role of the Quaternary Nitrogen

We have previously described the remarkable capacity of radioiodinated alkyl phospholipids to be sequestered and retained by a variety of tumors in vivo. We have already established the influence of certain structural parameters of iodinated alkyl phospholipids on tumor avidity, such as stereochemis...

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Bibliographic Details
Main Authors: Anatoly N. Pinchuk, Mark A. Rampy, Marc A. Longino, Ben Y. Durkee, Raymond E. Counsell, Jamey P. Weichert
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:Pharmaceutics
Subjects:
radioiodinated phospholipid ether analogs
alkyl phosphocholines
tumor imaging
Online Access:https://www.mdpi.com/1999-4923/15/1/171

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https://www.mdpi.com/1999-4923/15/1/171

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