Temporal Cortex Microarray Analysis Revealed Impaired Ribosomal Biogenesis and Hyperactivity of the Glutamatergic System: An Early Signature of Asymptomatic Alzheimer's Disease

Temporal Cortex Microarray Analysis Revealed Impaired Ribosomal Biogenesis and Hyperactivity of the Glutamatergic System: An Early Signature of Asymptomatic Alzheimer's Disease

Pathogenic aging is regarded as asymptomatic AD when there is no cognitive deficit except for neuropathology consistent with Alzheimer's disease. These individuals are highly susceptible to developing AD. Braak and Braak's theory specific to tau pathology illustrates that the brain's...

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Bibliographic Details
Main Authors: Ankita Kumari, Abdul Rahaman, Xin-An Zeng, Muhammad Adil Farooq, Yanyan Huang, Runyu Yao, Murtaza Ali, Romana Ishrat, Rafat Ali
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Neuroscience
Subjects:
microarray
Alzheimer
symptomatic
asymptomatic
genes
Online Access:https://www.frontiersin.org/articles/10.3389/fnins.2022.966877/full

Internet

https://www.frontiersin.org/articles/10.3389/fnins.2022.966877/full

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