MicroRNA miR-212-5p Regulates the MEK/ERK Signaling Pathway by Targeting A-Raf proto-oncogene serine/threonine-protein kinase (<i>ARAF</i>) to Regulate Cowshed PM<sub>2.5</sub>-Induced NR8383 Apoptosis

MicroRNA miR-212-5p Regulates the MEK/ERK Signaling Pathway by Targeting A-Raf proto-oncogene serine/threonine-protein kinase (<i>ARAF</i>) to Regulate Cowshed PM<sub>2.5</sub>-Induced NR8383 Apoptosis

<b>Objective:</b> To investigate the role of miR-212-5p-targeted <i>ARAF</i> during the apoptosis of rat alveolar macrophages induced by cowshed PM<sub>2.5</sub>. <b>Methods:</b> miRNA and related target genes and pathways were predicted using the KEGG...

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Bibliographic Details
Main Authors: Ke Sun, Yize Sun, Yunna Jia, Xinran Duan, Zhenhua Ma, Xiqing Zhang, Lixia Wang, Yanbin Zhu, Yunhang Gao, Wangdui Basang
Format: Article
Language:English
Published: MDPI AG 2023-12-01
Series:Toxics
Subjects:
cowshed PM<sub>2.5</sub>
miR-212-5p
mitochondrial damage
MEK/ERK signaling pathway
apoptosis
Online Access:https://www.mdpi.com/2305-6304/11/12/981

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https://www.mdpi.com/2305-6304/11/12/981

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