APC mutations dysregulate alternative polyadenylation in cancer
Abstract Background Alternative polyadenylation (APA) affects most human genes and is recurrently dysregulated in all studied cancers. However, the mechanistic origins of this dysregulation are incompletely understood. Results We describe an unbiased analysis of molecular regulators of poly(A) site...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2024-10-01
|
| Series: | Genome Biology |
| Online Access: | https://doi.org/10.1186/s13059-024-03406-4 |