SUFU suppresses ferroptosis sensitivity in breast cancer cells via Hippo/YAP pathway

SUFU suppresses ferroptosis sensitivity in breast cancer cells via Hippo/YAP pathway

Summary: Ferroptosis is a new kind of regulated cell death that is characterized by highly iron-dependent lipid peroxidation. Cancer cells differ in their sensitivity to ferroptosis. Here we showed that the Suppressor of fused homolog (SUFU), a critical component in Hedgehog signaling, regulates fer...

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Bibliographic Details
Main Authors: Kun Fang, Sha Du, Dachuan Shen, Zhipeng Xiong, Ke Jiang, Dapeng Liang, Jianxin Wang, Huizhe Xu, Lulu Hu, Xingyue Zhai, Yuting Jiang, Zhiyu Xia, Chunrui Xie, Di Jin, Wei Cheng, Songshu Meng, Yifei Wang
Format: Article
Language:English
Published: Elsevier 2022-07-01
Series:iScience
Subjects:
Cell biology
Functional aspects of cell biology
Cancer
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004222008902

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http://www.sciencedirect.com/science/article/pii/S2589004222008902

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