Neurogenesis and neuronal differentiation in the postnatal frontal cortex in Down syndrome

Neurogenesis and neuronal differentiation in the postnatal frontal cortex in Down syndrome

Abstract Although Down syndrome (DS), the most common developmental genetic cause of intellectual disability, displays proliferation and migration deficits in the prenatal frontal cortex (FC), a knowledge gap exists on the effects of trisomy 21 upon postnatal cortical development. Here, we examined...

पूर्ण विवरण

ग्रंथसूची विवरण
मुख्य लेखकों: Emma C. Utagawa, David G. Moreno, Kristian T. Schafernak, Nicoleta C. Arva, Michael H. Malek-Ahmadi, Elliott J. Mufson, Sylvia E. Perez
स्वरूप: लेख
भाषा:English
प्रकाशित: BMC 2022-06-01
श्रृंखला:Acta Neuropathologica Communications
विषय:
Down syndrome
Frontal cortex
Postnatal development
Calcium binding proteins
Neuronal maturation
ऑनलाइन पहुंच:https://doi.org/10.1186/s40478-022-01385-w

इंटरनेट

https://doi.org/10.1186/s40478-022-01385-w

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