M1 Macrophage-Biomimetic Targeted Nanoparticles Containing Oxygen Self-Supplied Enzyme for Enhancing the Chemotherapy

M1 Macrophage-Biomimetic Targeted Nanoparticles Containing Oxygen Self-Supplied Enzyme for Enhancing the Chemotherapy

Tumor hypoxia is considered one of the key causes of the ineffectiveness of various strategies for cancer treatment, and the non-specific effects of chemotherapy drugs on tumor treatment often lead to systemic toxicity. Thus, we designed M1 macrophage-biomimetic-targeted nanoparticles (DOX/CAT@PLGA-...

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Bibliographic Details
Main Authors: Jiayi Zhang, Bing Gu, Shimiao Wu, Lin Liu, Ying Gao, Yucen Yao, Degong Yang, Juan Du, Chunrong Yang
Format: Article
Language:English
Published: MDPI AG 2023-08-01
Series:Pharmaceutics
Subjects:
tumor microenvironment
M1 macrophage
tumor hypoxia
catalase
cancer treatment
Online Access:https://www.mdpi.com/1999-4923/15/9/2243

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https://www.mdpi.com/1999-4923/15/9/2243

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