Potential Benefits of Combining Proton or Carbon Ion Therapy with DNA Damage Repair Inhibitors

The use of charged particle radiotherapy is currently increasing, but combination therapy with DNA repair inhibitors remains to be exploited in the clinic. The high-linear energy transfer (LET) radiation delivered by charged particles causes clustered DNA damage, which is particularly effective in d...

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Bibliographic Details
Main Authors: Gro Elise Rødland, Mihaela Temelie, Adrian Eek Mariampillai, Sissel Hauge, Antoine Gilbert, François Chevalier, Diana I. Savu, Randi G. Syljuåsen
Format: Article
Language:English
Published: MDPI AG 2024-06-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/13/12/1058