Transcriptional Stress Induces Chromatin Relocation of the Nucleotide Excision Repair Factor XPG

Transcriptional Stress Induces Chromatin Relocation of the Nucleotide Excision Repair Factor XPG

Endonuclease XPG participates in nucleotide excision repair (NER), in basal transcription, and in the processing of RNA/DNA hybrids (R-loops): the malfunction of these processes may cause genome instability. Here, we investigate the chromatin association of XPG during basal transcription and after t...

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Bibliographic Details
Main Authors: Claudia Scalera, Giulio Ticli, Ilaria Dutto, Ornella Cazzalini, Lucia A. Stivala, Ennio Prosperi
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:International Journal of Molecular Sciences
Subjects:
XPG endonuclease
chromatin association
p300/CREBBP
R loop
acetylation
genome instability
Online Access:https://www.mdpi.com/1422-0067/22/12/6589

Internet

https://www.mdpi.com/1422-0067/22/12/6589

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