Blood-based epigenome-wide analyses of cognitive abilities

Blood-based epigenome-wide analyses of cognitive abilities

Abstract Background Blood-based markers of cognitive functioning might provide an accessible way to track neurodegeneration years prior to clinical manifestation of cognitive impairment and dementia. Results Using blood-based epigenome-wide analyses of general cognitive function, we show that indivi...

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Bibliographic Details
Main Authors: Daniel L. McCartney, Robert F. Hillary, Eleanor L. S. Conole, Daniel Trejo Banos, Danni A. Gadd, Rosie M. Walker, Cliff Nangle, Robin Flaig, Archie Campbell, Alison D. Murray, Susana Muñoz Maniega, María del C. Valdés-Hernández, Mathew A. Harris, Mark E. Bastin, Joanna M. Wardlaw, Sarah E. Harris, David J. Porteous, Elliot M. Tucker-Drob, Andrew M. McIntosh, Kathryn L. Evans, Ian J. Deary, Simon R. Cox, Matthew R. Robinson, Riccardo E. Marioni
Format: Article
Language:English
Published: BMC 2022-01-01
Series:Genome Biology
Subjects:
DNA methylation
EWAS
Cognitive ability
Prediction
Epidemiology
Online Access:https://doi.org/10.1186/s13059-021-02596-5

Internet

https://doi.org/10.1186/s13059-021-02596-5

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