Adipose-derived stem cell exosomes regulate Nrf2/Keap1 in diabetic nephropathy by targeting FAM129B

Adipose-derived stem cell exosomes regulate Nrf2/Keap1 in diabetic nephropathy by targeting FAM129B

Abstract Background Exosomes from adipose-derived stem cells (ADSCs-Exos) have exhibited a therapeutic role in diabetic nephropathy (DN). Further studies are needed to investigate how ADSCs-Exos regulate oxidative stress and inflammation in high glucose-induced podocyte injury. Methods An enzyme-lin...

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Bibliographic Details
Main Authors: Peiyao Ren, Fengmei Qian, Lanjun Fu, Wenfang He, Qiang He, Juan Jin, Danna Zheng
Format: Article
Language:English
Published: BMC 2023-07-01
Series:Diabetology & Metabolic Syndrome
Subjects:
Adipose-derived stem cells
Exosomes
Diabetic nephropathy
Oxidative stress
Inflammation
Nrf2/Keap1 pathway
Online Access:https://doi.org/10.1186/s13098-023-01119-5

Internet

https://doi.org/10.1186/s13098-023-01119-5

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