Altered activity of the medial prefrontal cortex and amygdala during acquisition and extinction of an active avoidance task

Altered medial prefrontal cortex (mPFC) and amygdala function is associated with anxiety-related disorders. While the mPFC-amygdala pathway has a clear role in fear conditioning, these structures are also involved in active avoidance. Given that avoidance perseveration represents a core symptom of a...

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Bibliographic Details
Main Authors: Xilu eJiao, Kevin D. Beck, Catherine E. Myers, Richard J Servatius, Kevin C.H. Pang
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-09-01
Series:Frontiers in Behavioral Neuroscience
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnbeh.2015.00249/full