Hybrid modeling of cell signaling and transcriptional reprogramming and its application in C. elegans development

Modeling of signal driven transcriptional reprogramming is critical for understanding of organism development, human disease, and cell biology. Many current modeling techniques discount key features of the biological sub-systems when modeling multi-scale, organism level processes. We present a mec...

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Bibliographic Details
Main Authors: Elana J Fertig, Ludmila V Danilova, Alexander V Favorov, Michael F Ochs
Format: Article
Language:English
Published: Frontiers Media S.A. 2011-11-01
Series:Frontiers in Genetics
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fgene.2011.00077/full