SETD2 regulates gene transcription patterns and is associated with radiosensitivity in lung adenocarcinoma

SETD2 regulates gene transcription patterns and is associated with radiosensitivity in lung adenocarcinoma

Lung adenocarcinoma (LUAD) has high morbidity and mortality worldwide, and its prognosis remains unsatisfactory. Identification of epigenetic biomarkers associated with radiosensitivity is beneficial for precision medicine in LUAD patients. SETD2 is important in repairing DNA double-strand breaks an...

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Bibliographic Details
Main Authors: Zihang Zeng, Jianguo Zhang, Jiali Li, Yangyi Li, Zhengrong Huang, Linzhi Han, Conghua Xie, Yan Gong
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Genetics
Subjects:
lung adenocarcinoma
radiosensitivity
SETD2
DNA damage response
multi-omics
prognosis
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2022.935601/full

Internet

https://www.frontiersin.org/articles/10.3389/fgene.2022.935601/full

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