An Efficient Synthesis of Optically Active [4-<sup>13</sup>C] Labelled Quorum Sensing Signal Autoinducer-2

A new synthetic route for the quorum sensing signal Autoinducer-2 (AI-2) is described and used for the preparation of [4-<sup>13</sup>C]-AI-2 starting from [1-<sup>13</sup>C]-bromoacetic acid. The key step in this process was the enantioselective reduction of an intermediate...

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Bibliographic Details
Main Authors: Osvaldo S. Ascenso, Gonzalo Carrau, Karina B. Xavier, M. Rita Ventura, Christopher D. Maycock
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/26/2/369