A genome-wide association study suggests the HLA Class II region as the major susceptibility locus for IgA vasculitis

A genome-wide association study suggests the HLA Class II region as the major susceptibility locus for IgA vasculitis

Abstract The genetic component of Immunoglobulin-A (IgA) vasculitis is still far to be elucidated. To increase the current knowledge on the genetic component of this vasculitis we performed the first genome-wide association study (GWAS) on this condition. 308 IgA vasculitis patients and 1,018 health...

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Main Authors: Raquel López-Mejías, F. David Carmona, Santos Castañeda, Fernanda Genre, Sara Remuzgo-Martínez, Belén Sevilla-Perez, Norberto Ortego-Centeno, Javier Llorca, Begoña Ubilla, Verónica Mijares, Trinitario Pina, José A. Miranda-Filloy, Antonio Navas Parejo, Diego de Argila, Maximiliano Aragües, Esteban Rubio, Manuel León Luque, Juan María Blanco-Madrigal, Eva Galíndez-Aguirregoikoa, David Jayne, Ricardo Blanco, Javier Martín, Miguel A. González-Gay
Format: Article
Language:English
Published: Nature Portfolio 2017-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-03915-2

Internet

https://doi.org/10.1038/s41598-017-03915-2

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