TLQP-21 is a low potency partial C3aR activator on human primary macrophages

TLQP-21 is a 21-amino acid neuropeptide derived from the VGF precursor protein. TLQP-21 is expressed in the nervous system and neuroendocrine glands, and demonstrates pleiotropic roles including regulating metabolism, nociception and microglial functions. Several possible receptors for TLQP-21 have...

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Bibliographic Details
Main Authors: Xaria X. Li, John D. Lee, Han S. Lee, Richard J. Clark, Trent M. Woodruff
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-01-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1086673/full