Effective Targeted Gene Knockdown in Mammalian Cells Using the piggyBac Transposase-based Delivery System

Nonviral gene delivery systems are rapidly becoming a desirable and applicable method to overexpress genes in various types of cells. We have recently developed a piggyBac transposase-based, helper-independent and self-inactivating delivery system (pmGENIE-3) capable of high-efficiency transfection...

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Bibliographic Details
Main Authors: Jesse B Owens, Juanita Mathews, Philip Davy, Ilko Stoytchev, Stefan Moisyadi, Rich Allsopp
Format: Article
Language:English
Published: Elsevier 2013-01-01
Series:Molecular Therapy: Nucleic Acids
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2162253116301950