Regulation of epidermal growth factor receptor signaling and erlotinib sensitivity in head and neck cancer cells by miR-7.

Elevated expression and activity of the epidermal growth factor receptor (EGFR)/protein kinase B (Akt) signaling pathway is associated with development, progression and treatment resistance of head and neck cancer (HNC). Several studies have demonstrated that microRNA-7 (miR-7) regulates EGFR expres...

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Váldodahkkit: Felicity C Kalinowski, Keith M Giles, Patrick A Candy, Alishum Ali, Clarissa Ganda, Michael R Epis, Rebecca J Webster, Peter J Leedman
Materiálatiipa: Artihkal
Giella:English
Almmustuhtton: Public Library of Science (PLoS) 2012-01-01
Ráidu:PLoS ONE
Liŋkkat:http://europepmc.org/articles/PMC3480380?pdf=render