Inferring clonal structure in HTLV-1-infected individuals: towards bridging the gap between analysis and visualization

Inferring clonal structure in HTLV-1-infected individuals: towards bridging the gap between analysis and visualization

Abstract Background Human T cell leukemia virus type 1 (HTLV-1) causes adult T cell leukemia (ATL) in a proportion of infected individuals after a long latency period. Development of ATL is a multistep clonal process that can be investigated by monitoring the clonal expansion of HTLV-1-infected cell...

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Bibliographic Details
Main Authors: Amir Farmanbar, Sanaz Firouzi, Wojciech Makałowski, Masako Iwanaga, Kaoru Uchimaru, Atae Utsunomiya, Toshiki Watanabe, Kenta Nakai
Format: Article
Language:English
Published: BMC 2017-07-01
Series:Human Genomics
Subjects:
Data-driven modeling
Adult T cell leukemia
Human T cell leukemia virus type 1
Integration site
Clonal expansion
High-throughput sequencing
Online Access:http://link.springer.com/article/10.1186/s40246-017-0112-8

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http://link.springer.com/article/10.1186/s40246-017-0112-8

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