Proinflammatory Responses of 1-Nitropyrene against RAW264.7 Macrophages through Akt Phosphorylation and NF-κB Pathways

Proinflammatory Responses of 1-Nitropyrene against RAW264.7 Macrophages through Akt Phosphorylation and NF-κB Pathways

Air pollution is a major environmental and public health problem worldwide. A nitro-polycyclic aromatic hydrocarbon and the most abundant air pollutant in diesel engine exhaust, 1-nitropyrene (1-NP), is caused by the incomplete combustion of carbonaceous organic substances. Macrophages are effector...

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Bibliographic Details
Main Authors: Ping-Kun Tsai, Shih-Pin Chen, Rosa Huang-Liu, Chun-Jung Chen, Wen-Ying Chen, Yan-Yan Ng, Yu-Hsiang Kuan
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:Toxics
Subjects:
1-nitropyrene
proinflammatory cytokines
PGE2
NF-κB pathway
Akt
Online Access:https://www.mdpi.com/2305-6304/9/11/276

Internet

https://www.mdpi.com/2305-6304/9/11/276

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