VEGF-A isoforms program differential VEGFR2 signal transduction, trafficking and proteolysis

VEGF-A isoforms program differential VEGFR2 signal transduction, trafficking and proteolysis

Vascular endothelial growth factor A (VEGF-A) binding to the receptor tyrosine kinase VEGFR2 triggers multiple signal transduction pathways, which regulate endothelial cell responses that control vascular development. Multiple isoforms of VEGF-A can elicit differential signal transduction and endoth...

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Bibliographic Details
Main Authors: Gareth W. Fearnley, Gina A. Smith, Izma Abdul-Zani, Nadira Yuldasheva, Nadeem A. Mughal, Shervanthi Homer-Vanniasinkam, Mark T. Kearney, Ian C. Zachary, Darren C. Tomlinson, Michael A. Harrison, Stephen B. Wheatcroft, Sreenivasan Ponnambalam
Format: Article
Language:English
Published: The Company of Biologists 2016-05-01
Series:Biology Open
Subjects:
VEGF-A
VEGFR2
Endothelial
Trafficking
Online Access:http://bio.biologists.org/content/5/5/571

Internet

http://bio.biologists.org/content/5/5/571

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