A substitution in the ligand binding domain of the porcine glucocorticoid receptor affects activity of the adrenal gland.

Glucocorticoids produced in the adrenal cortex under the control of the hypothalamic-pituitary axis play a vital role in the maintenance of basal and stress-related homeostasis and influence health and well-being. To identify loci affecting regulation of the hypothalamic-pituitary-adrenal (HPA) axis...

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Bibliographic Details
Main Authors: Eduard Murani, Henry Reyer, Siriluck Ponsuksili, Stephan Fritschka, Klaus Wimmers
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3445511?pdf=render