Treatment with vascular endothelial growth factor-A worsens cognitive recovery in a rat model of mild traumatic brain injury

Treatment with vascular endothelial growth factor-A worsens cognitive recovery in a rat model of mild traumatic brain injury

Mild traumatic brain injury (mTBI) is a common and unmet clinical issue, with limited treatments available to improve recovery. The cerebrovascular system is vital to provide oxygen and nutrition to the brain, and a growing body of research indicates that cerebrovascular injury contributes to mTBI s...

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Bibliographic Details
Main Authors: Mujun Sun, Tamara L. Baker, Campbell T. Wilson, Rhys D. Brady, Richelle Mychasiuk, Glenn R. Yamakawa, Anh Vo, Trevor Wilson, Stuart J. McDonald, Sandy R. Shultz
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-10-01
Series:Frontiers in Molecular Neuroscience
Subjects:
concussion
cerebrovascular
VEGF-A
intracerebroventricular administration
neuroinflammation
hypoxia
Online Access:https://www.frontiersin.org/articles/10.3389/fnmol.2022.937350/full

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https://www.frontiersin.org/articles/10.3389/fnmol.2022.937350/full

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