Dynamic modeling of the cellular senescence gene regulatory network

Cellular senescence is a cell fate that prominently impacts physiological and pathophysiological processes. Diverse cellular stresses induce it, and dramatic gene expression changes accompany it. However, determining the interactions comprising the gene regulatory network (GRN) governing senescence...

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Bibliographic Details
Main Authors: José Américo Nabuco Leva Ferreira de Freitas, Oliver Bischof
Format: Article
Language:English
Published: Elsevier 2023-03-01
Series:Heliyon
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844023012148