Molecular processes mediating hyperhomocysteinemia-induced metabolic reprogramming, redox regulation and growth inhibition in endothelial cells

Molecular processes mediating hyperhomocysteinemia-induced metabolic reprogramming, redox regulation and growth inhibition in endothelial cells

Hyperhomocysteinemia (HHcy) is an established and potent independent risk factor for degenerative diseases, including cardiovascular disease (CVD), Alzheimer disease, type II diabetes mellitus, and chronic kidney disease. HHcy has been shown to inhibit proliferation and promote inflammatory response...

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Bibliographic Details
Main Authors: Michael Jan, Ramon Cueto, Xiaohua Jiang, Liu Lu, Jason Sardy, Xinyu Xiong, Justine E. Yu, Hung Pham, Mohsin Khan, Xuebing Qin, Yong Ji, Xiao-Feng Yang, Hong Wang
Format: Article
Language:English
Published: Elsevier 2021-09-01
Series:Redox Biology
Subjects:
Homocysteine
Global mRNA/miRNA expression
Endothelial injury
Metabolic reprogramming
Redox signaling
Inflammation
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231721001762

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http://www.sciencedirect.com/science/article/pii/S2213231721001762

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