SWATH Mass Spectrometry-Based CSF Proteome Profile of <i>GBA</i>-Linked Parkinson’s Disease Patients

SWATH Mass Spectrometry-Based CSF Proteome Profile of <i>GBA</i>-Linked Parkinson’s Disease Patients

β-glucocerebrosidase (<i>GBA</i>)-associated mutations are a significant risk factor for Parkinson’s disease (PD) that aggravate the disease pathology by upregulating the deposition of α-Synuclein (α-Syn). The resultant clinical profile varies for PD patients without <i>GBA</i&g...

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Bibliographic Details
Main Authors: Saima Zafar, Aneeqa Noor, Neelam Younas, Mohsin Shafiq, Matthias Schmitz, Isabel Wurster, Kathrin Brockmann, Thomas Gasser, Inga Zerr
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:International Journal of Molecular Sciences
Subjects:
β-glucocerebrosidase
proteomics
CSF
SWATH
α-synuclein
Online Access:https://www.mdpi.com/1422-0067/23/22/14166

Internet

https://www.mdpi.com/1422-0067/23/22/14166

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