Fingolimod protects against neurovascular unit injury in a rat model of focal cerebral ischemia/reperfusion injury

Fingolimod protects against neurovascular unit injury in a rat model of focal cerebral ischemia/reperfusion injury

Recent research on the underlying mechanisms of cerebral ischemia indicates that the neurovascular unit can be used as a novel subject for general surveys of neuronal damage and protein mechanisms. Fingolimod (FTY-720) is a newly developed immunosuppressant isolated from Cordyceps sinensis that exhi...

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Bibliographic Details
Main Authors: Xiao-Yu Zhu, Ting-Ting Ma, Yang Li, Ming-Qi Zhang, Liang Zhao, Jia Liang, Lian-Qiu Min
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2023-01-01
Series:Neural Regeneration Research
Subjects:
astrocyte; blood-brain barrier; claudin-5; fty-720; interleukin-17a; ischemic stroke; neural protection; neurovascular unit; occludin; sphingosine-1-phosphate receptor 1
Online Access:http://www.nrronline.org/article.asp?issn=1673-5374;year=2023;volume=18;issue=4;spage=869;epage=874;aulast=Zhu

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http://www.nrronline.org/article.asp?issn=1673-5374;year=2023;volume=18;issue=4;spage=869;epage=874;aulast=Zhu

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