Inclusion Complexes of Rifampicin with Native and Derivatized Cyclodextrins: <i>In Silico</i> Modeling, Formulation, and Characterization

Inclusion Complexes of Rifampicin with Native and Derivatized Cyclodextrins: <i>In Silico</i> Modeling, Formulation, and Characterization

Inclusion complexation of rifampicin (RIF) with several types of cyclodextrins (βCD, hydroxypropyl-βCD, γCD, hydroxypropyl-γCD) in aqueous solutions at different pH values was investigated to assess the interactions between RIF and cyclodextrins (CDs). Molecular modeling was performed to determine t...

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Bibliographic Details
Main Authors: Qonita Kurnia Anjani, Juan Domínguez-Robles, Emilia Utomo, María Font, María Cristina Martínez-Ohárriz, Andi Dian Permana, Álvaro Cárcamo-Martínez, Eneko Larrañeta, Ryan F. Donnelly
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Pharmaceuticals
Subjects:
rifampicin
cyclodextrin
inclusion complexation
characterization
molecular docking
Online Access:https://www.mdpi.com/1424-8247/15/1/20

Internet

https://www.mdpi.com/1424-8247/15/1/20

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