A Kmer-based paired-end read de novo assembler and genotyper for canine MHC class I genotyping

Summary: The major histocompatibility complex class I (MHC-I) genes are highly polymorphic. MHC-I genotyping is required for determining the peptide epitopes available to an individual’s T-cell repertoire. Current genotyping software tools do not work for the dog, due to very limited known canine al...

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Bibliographic Details
Main Authors: Yuan Feng, Paul R. Hess, Stephen M. Tompkins, William H. Hildebrand, Shaying Zhao
Format: Article
Language:English
Published: Elsevier 2023-02-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004223000731