Endothelin potentiates TRPV1 via ET<sub>A </sub>receptor-mediated activation of protein kinase C

<p>Abstract</p> <p>Background</p> <p>Endothelin-1 (ET-1) both stimulates nociceptors and sensitizes them to noxious stimuli, an effect probably mediated by the ET<sub>A </sub>receptor (ET<sub>A</sub>R) expressed in sensory neurons. The cellular m...

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Bibliographic Details
Main Authors: Furkert Jens, Schaefer Michael, Eichhorst Jenny, Mousa Shaaban S, Kepura Frauke, Zöllner Christian, Plant Tim D, Stein Christoph, Oksche Alexander
Format: Article
Language:English
Published: SAGE Publishing 2007-11-01
Series:Molecular Pain
Online Access:http://www.molecularpain.com/content/3/1/35