The Time Course of MHC-I Expression in C57BL/6J and A/J Mice Correlates with the Degree of Retrograde Gliosis in the Spinal Cord following Sciatic Nerve Crush

The Time Course of MHC-I Expression in C57BL/6J and A/J Mice Correlates with the Degree of Retrograde Gliosis in the Spinal Cord following Sciatic Nerve Crush

The pleiotropic role of the major histocompatibility complex class I (MHC-I) reflects the close association between the nervous and immune systems. In turn, MHC-I upregulation postinjury is associated with a better regenerative outcome in isogenic mice following peripheral nerve damage. In the prese...

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Bibliographic Details
Main Authors: Bruno Henrique de Melo Lima, André Luis Bombeiro, Luciana Politti Cartarozzi, Alexandre Leite Rodrigues de Oliveira
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Cells
Subjects:
axotomy
sciatic nerve
nerve regeneration
plasticity
Online Access:https://www.mdpi.com/2073-4409/11/23/3710

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https://www.mdpi.com/2073-4409/11/23/3710

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