The temporal trend of placebo response in migraine prevention from 1990 to 2021: a systematic literature review and meta-analysis with regression

Abstract Background Migraine affects 1.1 billion people globally and is the second leading cause of disability worldwide. In clinical trials, treatment efficacy is evaluated by comparing the differential responses in the treatment and placebo arms. Although placebo response in preventive migraine tr...

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Bibliographic Details
Main Authors: Stewart J. Tepper, Jessica Cirillo, Edward Kim, Gil L’Italien, Julie M. Tweedie, Kunal Lodaya, Dushon Riley, Farah Pathan, Nicholas Antaki, Brian H. Nathanson, Peter McAllister
Format: Article
Language:English
Published: BMC 2023-05-01
Series:The Journal of Headache and Pain
Subjects:
Online Access:https://doi.org/10.1186/s10194-023-01587-0