Synthesis, Antimicrobial and Hypoglycemic Activities of Novel N-(1-Adamantyl)carbothioamide Derivatives

Synthesis, Antimicrobial and Hypoglycemic Activities of Novel N-(1-Adamantyl)carbothioamide Derivatives

The reaction of 1-adamantyl isothiocyanate 4 with the various cyclic secondary amines yielded the corresponding N-(1-adamantyl)carbothioamides 5a–e, 6, 7, 8a–c and 9. Similarly, the reaction of 4 with piperazine and trans-2,5-dimethylpiperazine in 2:1 molar ratio yielded the corresponding N,N'-...

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Bibliographic Details
Main Authors: Ebtehal S. Al-Abdullah, Hanaa M. Al-Tuwaijri, Hanan M. Hassan, Monirah A. Al-Alshaikh, Elsayed E. Habib, Ali A. El-Emam
Format: Article
Language:English
Published: MDPI AG 2015-05-01
Series:Molecules
Subjects:
adamantane derivatives
carbothioamides
antimicrobial activity
hypoglycemic activity
Online Access:http://www.mdpi.com/1420-3049/20/5/8125

Internet

http://www.mdpi.com/1420-3049/20/5/8125

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