Individualized detection of TMPRSS2-ERG fusion status in prostate cancer: a rank-based qualitative transcriptome signature

Individualized detection of TMPRSS2-ERG fusion status in prostate cancer: a rank-based qualitative transcriptome signature

Abstract Background TMPRSS2-ERG (T2E) fusion is highly related to aggressive clinical features in prostate cancer (PC), which guides individual therapy. However, current fusion prediction tools lacked enough accuracy and biomarkers were unable to be applied to individuals across different platforms...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser: Yawei Li, Hang Su, Kaidong Liu, Zhangxiang Zhao, Yuquan Wang, Bo Chen, Jie Xia, Huating Yuan, De-Shuang Huang, Yunyan Gu
Format: Artikel
Sprache:English
Veröffentlicht: BMC 2024-02-01
Schriftenreihe:World Journal of Surgical Oncology
Schlagworte:
Prostate cancer
Qualitative signature
TMPRSS2-ERG fusion
5-ERG-mRPs
Cross-platform
Online Zugang:https://doi.org/10.1186/s12957-024-03314-8

Online

https://doi.org/10.1186/s12957-024-03314-8

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