Multipurpose HTS Coagulation Analysis: Assay Development and Assessment of Coagulopathic Snake Venoms

Multipurpose HTS Coagulation Analysis: Assay Development and Assessment of Coagulopathic Snake Venoms

Coagulation assays currently employed are often low throughput, require specialized equipment and/or require large blood/plasma samples. This study describes the development, optimization and early application of a generic low-volume and high-throughput screening (HTS) assay for coagulation activity...

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Bibliographic Details
Main Authors: Kristina B. M. Still, Randjana S. S. Nandlal, Julien Slagboom, Govert W. Somsen, Nicholas R. Casewell, Jeroen Kool
Format: Article
Language:English
Published: MDPI AG 2017-11-01
Series:Toxins
Subjects:
snake venoms
blood coagulation
coagulation bioassay
high-throughput screening
mass spectrometry
liquid chromatography
Online Access:https://www.mdpi.com/2072-6651/9/12/382

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https://www.mdpi.com/2072-6651/9/12/382

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